Can chronic UTI cause interstitial cystitis?
William Rodriguez
Published Jan 19, 2026
Some people who have been diagnosed with BPS (interstitial cystitis), may have a long-term (chronic) urinary infection (UTI) in the bladder, which has not been picked up by current urine tests.
Can UTI trigger interstitial cystitis?
There are certain things that can trigger flares of IC, such as foods, drinks, and certain activities. UTIs are also known to trigger flares of IC, but it's not clear if they are a cause.
How do you tell if it's a UTI or interstitial cystitis?
The Difference Between a UTI and IC
In women who have interstitial cystitis, urine culture results will be negative, meaning that no bacteria are found in the urine as with a urinary tract infection. With IC, women may also experience pain during sexual intercourse, another symptom not commonly associated with a UTI.
What can trigger interstitial cystitis?
What causes interstitial cystitis (IC)?
- Autoimmune disease.
- Allergies.
- Defects in the lining of the bladder.
- Vascular (blood vessel) disease.
- Mast cell (cells that cause allergic symptoms) abnormalities.
- Presence of abnormal substances in the urine.
- Unidentified infections.
Does interstitial cystitis show up in a urine test?
How is interstitial cystitis diagnosed? No single test can diagnose IC. And symptoms of IC are a lot like those of other urinary disorders.
40 related questions foundWhat can mimic interstitial cystitis?
Since the symptoms of interstitial cystitis mimic other conditions, your physician may want to rule out the following before making a diagnosis:
- Kidney stone.
- Recurring urinary tract infection.
- Bladder cancer.
- Sexually transmitted diseases.
- Endometriosis (in women)
- Prostatitis (in men)
Can a gynecologist treat interstitial cystitis?
Managing a chronic illness like interstitial cystitis (IC) depends, in part, on your choice of doctor. Your primary care physician (PCP) may refer you to a specialist. A urologist is a doctor specializing in bladder diseases. Some gynecologists and urogynecologists (women's health doctors) also treat people with IC.
Do antibiotics help interstitial cystitis?
IC should not be confused with common cystitis, a bacterial infection of the bladder that is the most common type of urinary tract infection (UTI). Unlike common cystitis, interstitial cystitis is not caused by bacteria, nor does it respond to antibiotics.
Will interstitial cystitis ever go away?
For about half the cases, interstitial cystitis goes away by itself. Among those who need treatment, most find relief and get their lives back to normal.
Why do I have UTI symptoms but no infection?
Interstitial cystitis (IC)/bladder pain syndrome (BPS) is a chronic bladder health issue. It is a feeling of pain and pressure in the bladder area. Along with this pain are lower urinary tract symptoms which have lasted for more than 6 weeks, without having an infection or other clear causes.
Are there stages of interstitial cystitis?
Excessive frequency of urination, urinary urgency, and urethra, bladder or pelvic pain are common symptoms. Treatment is divided into five phases, ranging from lifestyle changes to injections to surgery.
Can interstitial cystitis get worse over time?
The symptoms of IC may stay the same over time or get worse. Some patients may go into remission for extended periods.
Can bladder be inflamed after UTI?
Bladder infections can lead to inflammation of the bladder (cystitis). Symptoms include pain and burning with urination, increased frequency of urination and sometimes abdominal pain. The inflammation usually improves after a course of antibiotics.
What makes interstitial cystitis worse?
Interstitial cystitis can flare up as a result of physical exercise, during a menstrual cycle, and psychological stress. Exercises such as a riding in a car, traveling in an airplane, and working out can cause a flare of interstitial cystitis symptomatology.
Is IC an autoimmune disease?
Interstitial cystitis (IC) is an autoimmune related condition that causes discomfort or pain in the bladder and a need to urinate frequently and urgently. It is far more common in women than in men.
How can I rebuild my bladder lining?
Pentosan polysulfate sodium is the only FDA-approved oral medication for interstitial cystitis. The drug binds to the walls of the bladder, helping replace and repair the lining. Symptom improvement can take up to six months, but several studies have shown moderately positive results.
What happens if interstitial cystitis goes untreated?
Lower quality of life. Frequent urination and chronic pain may interfere with everyday life. Sexual intimacy problems. Frequent urination and pain may strain sexual intimacy.
How long does interstitial cystitis last?
Over time symptoms increase and pain cycles may appear and last for 3-14 days. When these cycles become more frequent and last longer they are likely to be referred to a specialist. The most common misdiagnosis is urinary infection followed by yeast vaginitis, endometriosis and vulvodynia.
Why won't my cystitis go away?
Sometimes, persistent UTI-like symptoms may indicate another issue, such as antibiotic resistance, improper treatment, or an underlying condition. It's always important to reach out to your doctor if you're concerned about UTI symptoms that don't resolve with antibiotic treatment.
Why do I feel like I have cystitis all the time?
It is usually caused by a urine infection. Some women have repeated bouts of cystitis. Doctors define a recurrent infection as either three proven separate infections in a year or as two in six months. In many cases there is no apparent reason for a woman to get frequent attacks of cystitis.
How do urologists treat interstitial cystitis?
Bladder instillation for interstitial cystitis (also called a bladder wash or bath), a procedure in which the bladder is filled with a therapeutic solution that is retained in the bladder for varying periods of time, from a few seconds to 15 minutes, before it is drained through a catheter.
Who can diagnose interstitial cystitis?
Cystoscopy. Doctors may use cystoscopy to look inside the urethra and bladder. Doctors use a cystoscope, a tubelike instrument, to look for bladder ulcers, cancer, swelling, redness, and signs of infection. A doctor may perform a cystoscopy to diagnose interstitial cystitis (IC).
What is the latest treatment for interstitial cystitis?
Dimethylsulfoxide — Dimethylsulfoxide (DMSO) is a liquid medication that has been approved by the US Food and Drug Administration (FDA) to treat interstitial cystitis/bladder pain syndrome (IC/BPS).
What is IC belly?
During flares, patients may also experience the “IC Belly,” a sudden and random swelling of the lower abdomen. When an IC bladder is examined using a procedure called hydrodistention with cystoscopy, physicians often find small, bleeding wounds, also known as petechial hemorrhages or glomerulations.
Can an ultrasound detect interstitial cystitis?
No known radiographic, ultrasonographic, or other imaging findings are specific for interstitial cystitis. Unless indicated to help exclude alternative diagnoses, radiographic studies have only a limited role in the evaluation of interstitial cystitis.