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Can Sjogren's cause Hashimoto's?

Author

Emily Sparks

Published Jan 10, 2026

In a study of 170 patients with Hashimoto's thyroiditis, 17% had Sjögren's syndrome. In another retrospective study of patients with primary Sjögren's syndrome, the frequency of Hashimoto's thyroiditis was three to six times that of the general population.

Can sjogrens cause thyroid problems?

Patients with Sjogren's syndrome are often associated with hypothyroidism, and these patients may have more severe immune disorders, anemia, leukopenia, and renal involvement.

What other autoimmune diseases are associated with Sjogren's syndrome?

In secondary Sjogren's syndrome, which accounts for over 50% of the cases diagnosed, other autoimmune diseases are present, including rheumatoid arthritis (20-30%), systemic lupus erythematosus (15-35%), systemic sclerosis (10-25%), and psoriatic arthritis.

What autoimmune diseases are associated with Hashimoto's?

Hashimoto's disease can increase the risk of developing other autoimmune disorders, including:

  • Rheumatoid arthritis.
  • Addison's disease.
  • Graves' disease.
  • Type 1 diabetes.
  • Lupus.
  • Pernicious anemia.
  • Vitiligo.
  • Thrombocytopenic purpura.

What is the underlying cause of Hashimoto's disease?

Hashimoto's disease is an autoimmune disorder. The immune system creates antibodies that attack thyroid cells as if they were bacteria, viruses or some other foreign body. The immune system wrongly enlists disease-fighting agents that damage cells and lead to cell death.

31 related questions found

What is the life expectancy of someone with Hashimoto's thyroiditis?

With early diagnosis, timely institution of levothyroxine replacement therapy, informed patient follow-up care, and attention to other attendant complications, the prognosis in Hashimoto thyroiditis is excellent, with patients leading a normal life.

Does Hashimoto's mean I'm immunocompromised?

However, the immune system is complex, and having autoimmune thyroid disease does not mean that a person is immunocompromised or will be unable to fight off a viral infection.

Can you have Hashimoto's disease with normal thyroid levels?

Having only the TPO antibodies present with normal TSH and free T4 levels means that your thyroid is functioning normally and you don't have hypothyroidism, but it does mean that you may have Hashimoto's disease. Remember that Hashimoto's doesn't always cause hypothyroidism.

Does Hashimoto's show up on ANA test?

Positive ANA using the widely accepted HEp-2 method were commonly found in both Graves' disease and Hashimoto's thyroiditis. No evidence of subclinical systemic autoimmune disease was found, either by specific autoantibody tests or by increased frequency of rheumatologic symptoms or signs.

Do you still have Hashimoto's if your thyroid is removed?

Hashimoto's disease is a thyroid condition that causes the formation of antibodies that attack the thyroid gland. Thyroidectomy reduces thyroid antibody titers by an average of 92 percent, so the symptoms of Hashimoto's go away without a thyroid gland.

What does a Sjogren's flare feel like?

Joint pain is one of the most common symptoms of Sjögren's syndrome. Multiple joints are painful, usually episodically with periods of joint pain, known as “flares”, followed by periods of little or no joint pain. Tenderness and swelling of the joints, when present, are indicative of inflammatory arthritis.

What does Sjogren's fatigue feel like?

Sjogren's Syndrome patients often complain of mental fatigue or “brain fog.” Brain fog impairs focus, causes fuzzy concentration, and contributes to difficulty in problem-solving.

What are the hallmark symptoms of Sjögren's syndrome?

The hallmark symptoms of Sjögren's syndrome are extreme dry eyes and mouth. Some people also experience joint pain, swelling and/or stiffness. Sjögren's syndrome that occurs by itself is called primary Sjögren's syndrome.

Is Hashimoto's an autoimmune condition?

Hashimoto's thyroiditis can cause your thyroid to not make enough thyroid hormone. It is an autoimmune disease. It occurs when your body makes antibodies that attack the cells in your thyroid. Symptoms may include an enlarged thyroid gland (goiter), tiredness, weight gain, and muscle weakness.

Are there any new treatments for Sjogren's syndrome?

Several new, potentially disease-modifying drugs in the pipeline have renewed clinical optimism. St. Clair says existing treatment options include sialagogues such as pilocarpine and cevimeline that are approved by the US Food and Drug Administration for the treatment of glandular manifestations of Sjögren syndrome.

Can Sjogren's cause hyperthyroidism?

Conclusions In our study, we found that 9.8% of patients with Sjogren's syndrome could be associated with subclinical hypothyroidism and 3.9% with hyperthyroidism what can mask the clinical manifestations at the time of diagnosis.

What TSH level indicates Hashimoto's disease?

You're diagnosed with overt hypothyroidism when your thyroid-stimulating hormone (TSH) level is elevated (generally above 4.5 mIU/L, depending on the laboratory) and your free thyroxine (T4) level is low (under 0.8 ng/dL).

What blood test shows Hashimoto?

Anti-thyroid antibodies (ATA) tests, such as the microsomal antibody test (also known as thyroid peroxidase antibody test) and the anti-thyroglobulin antibody test, are commonly used to detect the presence of Hashimoto's thyroiditis.

Can you have both Hashimoto's and Graves disease?

Graves' disease and Hashimoto's thyroiditis can coexist in the same individual, reflecting their common autoimmune origin. Simultaneous occurrence of Graves' disease and Hashimoto's thyroiditis can result in clinical masking of one disorder by the other.

Do you treat Hashimoto's if TSH is normal?

There is ton's of research end evidence that Levothyroxine treatment in Hashimoto's patient with even normal TSH has a huge benefit of decreasing the autoimmune response and slowing down of progression of the disease as well as minimising the real risks of developing secondary autoimmune disease ( i.e. celiac disease, ...

How do I know if my hypothyroidism is Hashimoto's?

To determine if Hashimoto's disease is the cause of hypothyroidism, your health care provider will order an antibody test. The intended purpose of an antibody is to flag disease-causing foreign agents that need to be destroyed by other actors in the immune system.

Can you get the Covid vaccine if you have Hashimoto's?

The text says that persons suffering from autoimmune diseases face a big dilemma when it comes to vaccination, because, at least for now, vaccination is not recommended in their cases, especially for the most numerous group with Hashimoto's thyroiditis, an autoimmune disease of the thyroid gland caused by the immune ...

How serious is Hashimoto's disease?

If Hashimoto's is left untreated, complications can be life-threatening. Because the hormones produced by the thyroid are so vital to the body's functions, untreated Hashimoto's can lead to serious and even life-threatening complications.

Does everyone with hypothyroidism have Hashimoto's?

The short answer... it depends... Hashimoto's and hypothyroidism are not the same thing. Hashimoto's thyroiditis is one of many possible causes of hypothyroidism. Most people with Hashimoto's, also known as chronic autoimmune thyroiditis, have auto-antibodies that attack and destroy cells in the thyroid gland.

What foods should you avoid with Hashimoto's?

Foods to Avoid

On the autoimmune protocol diet, you remove all grains, legumes, nightshades (such as eggplant and peppers), dairy, eggs, coffee, alcohol, sugar, oil and food additives from your diet.