Can you mix cyclobenzaprine and ketorolac?
Noah Mitchell
Published Jan 06, 2026
Interactions between your drugs
What can you not mix with ketorolac?
Do not take aspirin or other NSAIDs such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn) while you are taking ketorolac. Also tell your doctor if you have or have ever had ulcers or bleeding in your stomach or intestines.
Can I take a muscle relaxer with Toradol?
Interactions between your drugs
No interactions were found between Flexeril and Toradol.
What meds Cannot be taken with cyclobenzaprine?
Do not use cyclobenzaprine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.
What drugs interact with ketorolac?
Some products that may interact with this drug include: aliskiren, ACE inhibitors (such as captopril, lisinopril), angiotensin II receptor blockers (such as losartan, valsartan), lithium, methotrexate, probenecid, corticosteroids (such as prednisone), other medications that may affect the kidneys (including cidofovir, ...
31 related questions foundWhat does cyclobenzaprine interact with?
Some products that may interact with this drug include: tricyclic antidepressants (such as amitriptyline, imipramine). Taking MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction.
Why can't you lay down after taking ketorolac?
Take this medicine with a full glass of water. Also, do not lie down for about 15 to 30 minutes after taking it. This helps to prevent irritation that may lead to trouble in swallowing.
Can you take pain medicine and muscle relaxers together?
Do not take both medications at the same time. Take your pain medication first, following all instructions and reading the label prior to use. You'll be more comfortable if you take the muscle relaxant about an hour later.
Can you take 2 cyclobenzaprine at once?
Official Answer. The maximum dose of cyclobenzaprine is 10mg three times a day. The usual recommended dose for muscle spasm is 5mg three times a day. Cyclobenzaprine should not be taken for longer than 2 to 3 weeks.
What should you not take with muscle relaxers?
Muscle relaxers, or muscle relaxants, are medications used to treat muscle spasms or muscle spasticity.
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You should not take muscle relaxants with:
- alcohol.
- CNS depressant drugs, such as opioids or psychotropics.
- sleeping medications.
- herbal supplements such as St. John's wort.
Can I take a muscle relaxer with ketorolac?
Interactions between your drugs
No interactions were found between cyclobenzaprine and ketorolac. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
How fast does ketorolac work?
When given IM or IV, Toradol starts working quickly (about 30 minutes after administration). Its effects can last up to 6 hours, and its full impact is usually felt after about 1 to 2 hours. Toradol is often prescribed for acute migraines and post-surgery pain.
Is ketorolac a strong medication?
Toradol is a nonsteroidal non-inflammatory drug (NSAID). It's not a narcotic. Toradol (generic name: ketorolac) is not addictive, but it's a very strong NSAID and can lead to serious side effects. You also shouldn't take it for long periods of time.
Is ketorolac good for back pain?
Based on comparable efficacy and a superior adverse event profile, ketorolac was preferable to acetaminophen with codeine for the treatment of acute low back pain in the ED.
Why is ketorolac limited to 5 days?
Dose of Toradol is not to exceed 5 days, because of increased risk of adverse effects. Oral Toradol is indicated only as a continuation therapy to IV/IM, and the combined duration of use of oral and IV/IM is not to exceed 5 days. The recommended total daily oral dose of Toradol is 40 mg maximum.
Can I take ketorolac 10 mg and Tylenol?
The risk will depend on how much of each medicine you take every day, and on how long you take the medicines together. Therefore, do not take acetaminophen (e.g., Tylenol) together with ketorolac for more than a few days, unless otherwise directed by your medical doctor or dentist.
What is the strongest muscle relaxer medication?
Metaxalone. Metaxalone is a muscle relaxant suitable for sprains, strains, and other muscle-based pain.
Is 10 mg of cyclobenzaprine strong?
The usual starting dose, according to the Drug Enforcement Administration, is 5 mg three times a day. The maximum recommended dose is 10 mg three times a day. Patients typically feel better within 10 days.
How long does it take for cyclobenzaprine to kick in?
Some people start to feel the effects within 30 minutes, but you should definitely feel the effects within an hour. The long-acting Amrix (cyclobenzaprine) capsules take a little longer to work but last for up to 24 hours. Most people start to feel the effects about a hour and a half after they take their dose.
What pain medication can you take with cyclobenzaprine?
Cyclobenzaprine works by blocking nerve impulses that you recognize as pain and is often combined with over-the-counter (OTC) pain medications like:
- acetaminophen (Tylenol)
- anti-inflammatory NSAIDs like ibuprofen (Advil, Motrin) or naproxen (Aleve).
What is the safest muscle relaxer?
Taken as 800 mg tablets 3 to 4 times a day, metaxalone (Skelaxin) has the fewest reported side effects and lowest sedation potential of the muscle relaxants based on clinical studies. Simply put, it is the best-tolerated of the muscle relaxants.
Do muscle relaxers help with pain?
Muscle relaxers are used in addition to rest, physical therapy, and other measures to relieve discomfort. They are typically prescribed for short-term use to treat acute, painful musculoskeletal conditions. Muscle relaxers are occasionally prescribed for chronic pain (pain lasting longer than 3 months).
How long does ketorolac last?
You'll feel the effects of a Toradol shot within minutes after the injection, especially compared to a pill or tablet. This makes it an effective pain reliever. It usually takes about six hours for Toradol to wear off.
How long does ketorolac stay in your system?
by Drugs.com
Ketorolac would be in your system for about 33 hours. The average elimination half-life of Ketorolac is 5 to 6 hours. This is the time it takes for your body to reduce the plasma levels by half. It takes about 5.5 x elimination half-life before a drug is totally eliminated from your system.
Does ketorolac cause drowsiness?
Ketorolac may cause some people to become dizzy or drowsy. If either of these side effects occurs, do not drive, use machines, or do anything else that could be dangerous if you are not alert. Serious side effects can occur during treatment with this medicine.