How does Indocin make you feel?
Rachel Ellis
Published Jan 19, 2026
Upset stomach, heartburn, headache, drowsiness, or dizziness may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
Can indomethacin make you feel weird?
This medicine may cause some people to become dizzy, lightheaded, drowsy, or less alert than they are normally. Even if taken at bedtime, it may cause some people to feel drowsy or less alert on arising.
Does Indocin work immediately?
This medicine usually begins to work within 1 week, but in severe cases up to two weeks or even longer may pass before you begin to feel better.
What happens when you take indomethacin?
Indomethacin is in a class of medications called NSAIDs. It works by stopping the body's production of a substance that causes pain, fever, and inflammation.
How quickly does Indocid work?
The suppository takes about one hour to be completely absorbed and do its work. If you are not sure how to use a suppository, ask your doctor or pharmacist.
16 related questions foundDoes Indocin make sleepy?
This medicine may cause some people to become dizzy, lightheaded, drowsy, or less alert than they are normally. Even if taken at bedtime, it may cause some people to feel drowsy or less alert on arising.
Is Indocin a painkiller?
Indomethacin is used to relieve pain, swelling, and joint stiffness caused by arthritis, gout, bursitis, and tendonitis. It is also used to relieve pain from various other conditions. This medication is known as a nonsteroidal anti-inflammatory drug (NSAID).
Is indomethacin a strong drug?
Indomethacin is one of the most potent NSAIDs and is generally only used after other NSAIDs have proved ineffective. NSAIDs (including indomethacin) have been associated with an increased risk of stroke or heart attack.
Does indomethacin affect sleep?
Previous studies have demonstrated that some nonsteroidal anti-inflammatory drugs (NSAIDs), specifically aspirin and indomethacin, have acute negative effects on sleep in humans and animals.
Is Indocin a narcotic?
If you experience any mental health changes, including anxiety, while taking this medication, contact your provider. Is indomethacin (Indocin) a controlled substance? No, indomethacin (Indocin) is not a controlled substance.
Is Indocin stronger than Celebrex?
Conclusion: High-dose celecoxib (800/400 mg) was significantly more effective than low-dose celecoxib (50 mg bid) and comparable to indomethacin in the treatment of moderate to extreme pain in patients with acute gouty arthritis. Further, celecoxib was well tolerated.
Is Indocin the same as ibuprofen?
Indocin and ibuprofen provide similar pain relief when used in arthritis patients. 6 A study that compared the drugs found that they were similarly effective, but patients preferred Indocin, although the study authors did not say why.
What painkiller can I take with indomethacin?
Yes, you can take Tylenol while taking indomethacin. As long as you do not exceed the recommended daily doses you can safely alternate the medicines, or take together for added pain relief. The usual dose of indomethacin for pain in adults is 20mg 3 times a day or 40mg 2 to three times a day.
Does indomethacin cause anxiety?
Results: Thirty-two patients experienced a psychiatric reaction after receiving indomethacin for postpartum pain. The symptoms were often severe and included dizziness, anxiety, fear, agitation, affective lability, depersonalization, paranoia, and hallucinations.
Can indomethacin make you depressed?
Discussion. The central nervous system (CNS) side effects of indomethacin include cognitive dysfunction, depression depersonalisation, hallucination, and psychosis. 1-4 Though psychosis is less common it is the most serious CNS side effect of indomethacin.
What are the side effects of Indocin?
Serious side effects of Indocin may include heart attack, stroke, skin changes (paleness, blisters, rash, and hives), weight gain, swelling, shortness of breath, tachycardia, unusual bleeding (including GI bleeding), jaundice, stomach pain, and pain with urination, bloody urine, blurry vision, and back pain.
Does indomethacin make you nauseous?
Side effects that you should report to your doctor or health care professional as soon as possible: allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue. difficulty breathing or wheezing. nausea, vomiting.
Does diclofenac make you sleepy?
It happens rarely, but some people can feel tired, dizzy or sleepy when they take diclofenac. They may also have problems with their eyesight.
What drug is similar to indomethacin?
- Naproxen.
- Indocin.
- Ibuprofen.
- Advil.
- Methylprednisolone.
- Aleve.
How long does Indocin stay in your system?
The mean half- life of indomethacin is estimated to be about 4.5 hours. With a typical therapeutic regimen of 25 or 50 mg t.i.d., the steady-state plasma concentrations of indomethacin are an average 1.4 times those following the first dose.
Is indomethacin stronger than diclofenac?
Results: Diclofenac sodium was a more effective analgesic than indomethacin suppositories for right mediolateral episiotomy pain.
Is Indocin good for back pain?
A short-term double-blind sequential trial of indomethacin against placebo in the treatment of low back pain, with and without nerve root pain such as sciatica, showed that indomethacin was significantly more effective than placebo in the group with nerve root pain.
What does Indocin cure?
Indocin is a prescription medicine used to treat the symptoms of inflammation and pain associated with osteoarthritis, rheumatoid arthritis, gouty arthritis or ankylosing spondylitis. Indocin may be used alone or with other medications.
Will indomethacin raise blood pressure?
The most widely studied of the NSAID medications is indomethacin, which has been shown to increase mean blood pressure by as much as 5 mm Hg in treated hypertensive patients.
Is indomethacin like Toradol?
Side effects of Indocin that are different from Toradol include a feeling of bowel fullness, rectal irritation, nervousness, skin rash, itching, and blurred vision. Side effects of Toradol that are different from Indocin include nausea, stomach pain, sweating, and ringing in the ears.