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How would you know if you had pancreatic insufficiency?

Author

Emma Payne

Published Jan 07, 2026

Diagnosis of pancreatic insufficiency

Pancreatic insufficiency is suspected in a patient who develops diabetes, upper abdominal pain and features of malabsorption. Bowel movements classically are bulky, loose and foul smelling; because of their oily nature, they may float in the toilet bowl, and are difficult to flush.

What are the first signs of pancreatic insufficiency?

What are the symptoms of exocrine pancreatic insufficiency (EPI)?

  • Abdominal pain, gas and bloating.
  • Constipation.
  • Diarrhea.
  • Fatty stools (pale, oily, foul-smelling poop that floats).
  • Unexplained weight loss or failure to thrive in infants and children.

How do you test for pancreatic insufficiency?

The 3 main EPI tests used to aid in diagnosis are:

  1. Fecal elastase test. This test measures the amount of elastase, an enzyme produced by the pancreas, in your stool. ...
  2. Fecal fat test. This test checks the amount of fat in your stool. ...
  3. Pancreatic function test.

How do I know if I have exocrine pancreatic insufficiency?

Foul-smelling, oily stools (steatorrhea)

People with EPI are not able to absorb all the fat that they eat, so undigested fat is excreted, resulting in stools that look oily or greasy. Not all people experience this symptom.

How do you fix pancreatic insufficiency?

Your doctor may start you on a prescription treatment called pancreatic enzyme replacement therapy, or PERT. PERTs are the main treatment for EPI—they replace the digestive enzymes that your pancreas isn't producing anymore. When taken with food, PERTs help break down the nutrients in food.

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What does EPI poop look like?

Foul-smelling, greasy stools (steatorrhea)

People with EPI cannot absorb all of the fat that they eat. The undigested fat that passes through the digestive system may cause oily or greasy-looking stools. These stools may also smell really bad, float, and be difficult to flush.

Is Pancreatic Insufficiency serious?

Damage to the cells producing pancreatic enzymes leads to exocrine pancreatic insufficiency, which is a serious problem leading to malnutrition, complications, and poor quality of life.

Does pancreatic insufficiency cause fatigue?

If left untreated, exocrine pancreatic insufficiency can lead to feeling malnourished, fatigued and weak. This is due to the poor absorption of vitamins and nutrients. Eventually, it can lead to thinning bones (osteoporosis) or anemia (a deficiency of red blood cells).

What foods should be avoided with pancreatic insufficiency?

Avoidfried, creamy, or cheesy foods, such as pastries. You'll also want to avoid trans fat, a hydrogenated oil and particularly unhealthy type of fat that's often found in packaged food, says Massey, and steer clear of alcohol. While it may take some planning, it's possible to eat a healthy, satisfying diet.

What happens if your pancreas doesn't produce enough enzymes?

In EPI, the pancreas does not produce enough of the enzymes needed to digest food. Without this breakdown, an individual cannot absorb the necessary nutrients and vitamins. This leads to diarrhea, vitamin deficiency, and weight loss.

Is there a blood test for pancreatic insufficiency?

If your signs and symptoms continue and a strong suspicion of pancreatic insufficiency remains, your healthcare practitioner may order stool tests for fecal fat and chymotrypsin or blood tests for amylase and lipase to look at other aspects of pancreas and digestive function.

Which disease is related to a malfunctioning pancreas?

With repeated bouts of acute pancreatitis, damage to the pancreas can occur and lead to chronic pancreatitis. Scar tissue may form in the pancreas, causing loss of function. A poorly functioning pancreas can cause digestion problems and diabetes.

Can pancreatitis go undiagnosed?

Pancreatitis can be dangerous if it goes undiagnosed and untreated. If you have the signs or symptoms of pancreatitis, you should seek medical attention.

What can cause pancreatic insufficiency?

What causes EPI?

  • Chronic pancreatitis. Chronic pancreatitis is inflammation of your pancreas that doesn't go away over time. ...
  • Acute pancreatitis. ...
  • Autoimmune pancreatitis. ...
  • Diabetes. ...
  • Surgery. ...
  • Genetic conditions. ...
  • Celiac disease. ...
  • Pancreatic cancer.

Does pancreatic insufficiency go away?

Exocrine pancreatic insufficiency (EPI) is a long-lasting medical condition that affects the pancreas. It usually upsets the way the body breaks down (digests) food and can cause gastrointestinal problems. Exocrine pancreatic insufficiency (EPI) may be managed, but it cannot be cured.

Do probiotics help with EPI?

Probiotics may be an especially good idea if you've been taking antibiotics, as they may help replenish the beneficial bacteria in your digestive tract that the antibiotics may have killed off along with the harmful bacteria that caused the infection.

What is the main organ of the body affected by EPI?

Exocrine pancreatic insufficiency (EPI) is a condition that happens when there's a problem with your pancreas, mainly with how well it helps you digest food. Your pancreas makes enzymes that break down the fats, proteins, and starches you eat so your body can use them.

Can you live a normal life with pancreatic insufficiency?

If your condition is well managed, it's possible to live a healthy life — even into your advanced years — when you have EPI.

What does pancreatic insufficiency feel like?

Pancreatic insufficiency is suspected in a patient who develops diabetes, upper abdominal pain and features of malabsorption. Bowel movements classically are bulky, loose and foul smelling; because of their oily nature, they may float in the toilet bowl, and are difficult to flush.

Can pancreatic insufficiency cause diarrhea?

“When the pancreas fails to produce the necessary digestive enzymes, fats and other nutrients can't be absorbed,” Agrawal explains. “Instead, they remain in the small bowel, drawing in water and causing diarrhea.”

Can pancreatic insufficiency cause chest pain?

The tumors make the body release extra amounts of a hormone called gastrin, which in turn makes the stomach release extra acid. Like EPI, it can lead to diarrhea. But unlike EPI, the most common symptom is burning pain between the chest and stomach.

Does pancreatitis cause gas?

Gas Is a Very Common Symptom of Pancreatitis

But flatulence that's accompanied by swelling in the abdomen, fever, nausea, and vomiting is not. These symptoms can be warning signs of pancreatitis — inflammation of the pancreas, which assists in the digestive process. Gas is a very common symptom of pancreatitis.

How is pancreatitis diagnosis?

Diagnosis

  1. Blood tests to look for elevated levels of pancreatic enzymes, along with white blood cells, kidney function and liver enzymes.
  2. Abdominal ultrasound to look for gallstones and pancreas inflammation.
  3. Computerized tomography (CT) scan to look for gallstones and assess the extent of pancreas inflammation.

Can pancreatic insufficiency cause constipation?

One of the telltale signs of exocrine pancreatic insufficiency (EPI) — a condition in which the pancreas fails to produce enough digestive enzymes — are loose, oily stools. But some people with EPI can also experience a very different symptom: intermittent constipation.

How can I tell if my pancreas is inflamed?

If you have acute pancreatitis, you may experience:

  1. Moderate to severe upper abdominal pain that may spread to your back.
  2. Pain that comes on suddenly or builds up over a few days.
  3. Pain that worsens when eating.
  4. Swollen, tender abdomen.
  5. Nausea and vomiting.
  6. Fever.
  7. Faster than usual heart rate.