Is a steroid shot the same as a cortisone shot?
Daniel Moore
Published Jan 21, 2026
Cortisone is medicine sometimes injected into the body to help ease pain and swelling from arthritis, injury or illness. Cortisone shots are sometimes called corticosteroid shots.
What is the difference between a steroid shot and a cortisone shot?
Also called “corticosteroid,” “steroid shot,” and a human-made version of the hormone cortisol, these shots aren't pain relievers. Cortisone is a type of steroid, a drug that lowers inflammation, which is something that can lead to less pain.
Is a cortisone injection a steroid?
Hydrocortisone injections contain the active ingredient hydrocortisone. This is a steroid (or corticosteroid). The injection releases the hydrocortisone slowly into the part of your body that is painful or swollen.
How long does a steroid shot last?
How long does cortisone injection last? The effect of a cortisone shot can last anywhere from 6 weeks to 6 months. As cortisone reduces inflammation, it can make you feel great. However, this effect is only temporary as cortisone does not cure the disease.
What are the side effects of steroid injections?
Potential side effects of steroid injections include:
- pain around the injection site, ranging from minor to intense pain, which is often called a cortisone or steroid flare.
- bruising around the injection site.
- face flushing for a few hours.
- thin or pale skin around the injection site.
- insomnia.
What is an alternative to a cortisone shot?
Enter – PRP, or platelet-rich plasma. PRP injections offer a viable alternative to corticosteroid injections, without all of the nasty side effects.
What is the downside of cortisone shots?
The Downsides
According to the National Institutes of Health, the side effects from cortisone shots include: Dizziness or headaches. Skin issues, including dryness, thinness, acne, dry skin, and red or purple blotches. Fatigue and trouble sleeping.
How quickly do steroid injections work?
A corticosteroid injection will usually take 3 to 7 days to begin to have a positive effect. It may take up to two weeks for the medicine to decrease the inflammation to a point where pain is improved. The full benefit of the corticosteroid may not be felt until 6 weeks after injection.
Do steroid shots weaken your immune system?
Systemic corticosteroid therapy may adversely affect both the innate and adaptive immune response. The ability of neutrophils to migrate to sites of infection is impaired by corticosteroids [4]. Macrophage and monocyte function may also be inhibited by corticosteroids [5].
How long after a cortisone shot can I walk?
The injection consists of two medications: Cortisone (a steroid) and Marcaine (a numbing agent). It is recommended that you refrain from any high level activities using your knee for approximately 48 hours. Routine activities including walking are permitted.
Does it hurt to get a cortisone shot?
Where Do Cortisone Shots Hurt the Most? Certain cortisone injections will hurt more than others based on their location. Injections into the palm of the hand and sole of the foot can be especially painful. Injections tend to hurt most when the cortisone is delivered to a small space.
What are the disadvantages and side effects of cortisone injections?
Risks
- Cartilage damage.
- Death of nearby bone.
- Joint infection.
- Nerve damage.
- Temporary facial flushing.
- Temporary flare of pain and inflammation in the joint.
- Temporary increase in blood sugar.
- Tendon weakening or rupture.
Is a steroid shot better than the pills?
Local injections are generally well-tolerated and are less likely to produce serious side effects than other forms of steroid medications. Steroid injections may help avoid the need for oral steroids or increased doses of oral steroids, which could have greater side effects.
What is a steroid injection good for?
Steroid injections, also called corticosteroid injections, are anti-inflammatory medicines used to treat a range of conditions. They can be used to treat problems such as joint pain, arthritis, sciatica and inflammatory bowel disease. Steroid injections are only given by healthcare professionals.
Can a cortisone shot affect your heart?
Prednisone and hydrocortisone are two examples of steroids. Yet well-known adverse effects of these potent anti-inflammatory medications can increase the risk of developing high blood pressure, diabetes, and obesity -- risk factors for heart disease.
Can I have a steroid injection during COVID-19?
Currently there is no evidence to suggest that a steroid injection to a joint or soft tissue will reduce the effectiveness of a COVID vaccine. For a non-essential steroid injection, it should be delayed for 2 weeks after the vaccination.
How long after steroids can I get Covid vaccine?
Can I have the vaccine if I am taking steroids? It's fine for you to have the vaccine while you're taking steroids. There's no reason to delay the vaccine if you're taking steroids, or have recently had a steroid injection or finished a course of steroid treatment.
What should I expect after a steroid shot?
The most common side effect of the treatment is temporary pain and swelling around the injection site. Some people may also experience some mild bruising or dimples around the area. Patients with chronic conditions such as diabetes or high blood pressure may not be the best candidates for the treatment.
What is the next step if a cortisone shot doesn't work?
If the first injection doesn't provide pain relief, your doctor may try a second injection four to six weeks later. If there's no improvement after the second injection, a third injection is not recommended.
What is the next step if steroid injection does not work?
When one (or several) injections fail to fix your problem, often the next recommended step is surgery. The majority of the people we work with are seeking pain relief for their back, knee, neck or shoulder WITHOUT the need for surgery and other procedures.
Does cortisone help arthritis?
Cortisone shots can treat both inflammatory arthritis and osteoarthritis, but they may be more effective at treating inflammatory arthritis than osteoarthritis, according to the Mayo Clinic. “For osteoarthritis, sometimes people don't get relief, and it's hard to predict why,” says Dr.
What are the pros and cons of a cortisone shot?
Corticosteroid injections may reduce pain and increase function (for the short term) but it does not mean they are good for the joint long term.
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Cons of IACSs
- joint pain and swelling.
- stiffness.
- weight gain.
- sleep disturbances.
- gastrointestinal issues.
- osteoporosis.
- pancreatitis.
Does cortisone cause weight gain?
Steroids affect your metabolism and how your body deposits fat. This can increase your appetite, leading to weight gain, and in particular lead to extra deposits of fat in your abdomen.
Can you get two cortisone shots at the same time in different areas?
Q: Is it possible to inject more than one body part at a time? A: Yes, it's possible to inject different parts of the body at the same time, but we have to look at the overall amount of cortisone we're injecting.
What is the difference between cortisone and steroid?
“Steroid” is short for corticosteroid, which is different from the hormone-related steroid compounds that some athletes use. You may hear them called cortisone injections, cortisone shots, steroid shots, or corticosteroid injections. Steroids ease inflammation and slow your immune system.