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What causes Nexplanon to fail?

Author

Emma Payne

Published Jan 19, 2026

Of the remaining 127 cases, the most common reason for unintended pregnancy was failure to insert the implant in 84 women. Other reasons included incorrect timing of insertion (19 cases), expulsion of Implanon (3 cases) and interaction with hepatic enzyme-inducing medicines (8 cases).

What makes Nexplanon less effective?

The common antibiotics a doctor or nurse gives you will not affect your Nexplanon. Antibiotics for TB (tuberculosis) and antibiotics to treat or prevent meningitis can affect Nexplanon as can some drugs used to treat epilepsy and HIV. The complementary medicine St John's Wort can also make Nexplanon less effective.

What can stop the implant from working?

Some medicines can make the implant less effective, such as:

  • medicines for HIV, epilepsy and tuberculosis.
  • complementary remedies, such as St John's Wort.
  • some antibiotics, such as rifabutin or rifampicin.

What can cause Nexplanon birth control to not work?

This effect can result in pregnancy. Examples include griseofulvin, modafinil, rifamycins (such as rifampin, rifabutin), St. John's wort, drugs used to treat seizures (such as barbiturates, carbamazepine, felbamate, phenytoin, primidone, topiramate), HIV drugs (such as nelfinavir, nevirapine, ritonavir), among others.

What are the chances of Nexplanon not working?

It has a 0.1% failure rate, meaning that 1 in 1,000 people using the birth control implant will become pregnant in a year. The implant prevents pregnancy better than male sterilization (vasectomy), which has a 0.15% failure rate and is often irreversible.

31 related questions found

How would you know if your pregnant on the implant?

Women who get pregnant while using birth control may notice the following signs and symptoms: a missed period. implantation spotting or bleeding. tenderness or other changes in the breasts.

How do I know if Im pregnant on Nexplanon?

It is very unlikely, but you can get pregnant while using this. Take a urine pregnancy test if you feel like you may be pregnant. Call the clinic right away if it is positive.

Does Nexplanon lose effectiveness over time?

Nexplanon prevents pregnancy by continually releasing a low dose of progestin over a three-year period. The amount of progestin released slowly decreases over time. By the end of the third year, the dose released is too small to prevent pregnancy, which is why the implant must be removed at that time.

What does Brown Discharge Mean while on Nexplanon?

You may also have brown discharge (old blood). This discharge is common as your body adjusts to the hormone medicine in the implant, which can take one or more months to stop.

What happens if you get pregnant on Nexplanon?

If you become pregnant while using NEXPLANON, you have a slightly higher chance that the pregnancy will be ectopic (occurring outside the womb) than do women who do not use birth control. Unusual vaginal bleeding or lower stomach (abdominal) pain may be a sign of ectopic pregnancy.

Can you get pregnant with the implant in your arm?

The implant is one of the most effective birth control methods out there — it's more than 99% effective. That means fewer than 1 out of 100 people who use the implant get pregnant each year. The implant works by releasing the hormone progestin into your body.

Can Nexplanon stop working before 3 years?

Nexplanon remains effective for three to four years. You will want to keep track of the scheduled removal date and make an appointment with your doctor to remove it just before the expiration date. Once it expires, it no longer protects against pregnancy.

Do you ovulate on Nexplanon?

The contraceptive implant is inserted beneath the skin of the upper arm. The implant releases a progestational hormone to prevent sperm from reaching the egg. The implant typically suppresses ovulation as well.

Is brown blood normal with Nexplanon?

The most common birth control implant side effect is spotting (light bleeding or brown discharge), especially in the first 6-12 months. Sometimes the implant causes long-term spotting, or periods can get longer and heavier.

Why do I have brown discharge but no period?

When there is no pregnancy, brown discharge may be caused by: old blood leaving the uterus a few days after the end of a period. a period just beginning to start, where the flow is very light. ovulation spotting, which may be pinkish-brown.

Why is there dark brown discharge?

It takes time for blood to flow from your cervix until you see it, and during this time, the blood gets older. The oxidation of that old blood makes it appear brown by the time it gets to your underwear. Following your period, brown discharge is in most cases simply blood that has taken a little longer to be expelled.

Does implant become less effective?

The implants themselves are not dangerous, but as the hormone levels in the implants drop, they become less and less effective. After they lose effectiveness, they may still release a small dose of hormone for several more years, which serves no purpose.

Can Nexplanon give a false positive?

Birth control cannot give you a false positive or a false negative. At-home pregnancy tests rely on a hormone called hCG to detect pregnancy. This hormone is not a component of any common birth control method including the pill or IUD.

Can you sue if you get pregnant on Nexplanon?

Under state and federal laws, it is possible to sue medical providers and drug companies for wrongful birth if contraceptives that were intended to prevent a pregnancy fail to work as directed.

Can Nexplanon cause a positive pregnancy test?

If you think that you might be pregnant then do a pregnancy test or speak to your doctor or nurse as soon as possible. Using the implant will not affect a pregnancy test. If you do get pregnant while you are using the implant there is no evidence that it will harm the baby.

When can you take a pregnancy test when on birth control?

Wait for the right time to take the test

For some, this may not be until the first day of your period. If you can wait until after your missed period, tests may be more accurate.

Can you have a miscarriage while on the implant?

Although it is extremely unlikely that you will become pregnant while using Nexplanon, if you do, there is a slightly higher risk of having an ectopic pregnancy, which is when an egg develops outside of the uterus and cannot develop normally, ending in a miscarriage.

Why is my pregnancy test line so faint?

The strength of the positive test line depends on how much hCG is in your urine. If the line is faint, it usually means that the hCG level is low. One reason why hCG levels may be low could be because you're still very early into your pregnancy.

Can the implant give you a false positive?

A chemical pregnancy is a miscarriage that happens before week five of the pregnancy when an embryo implants in your uterus but it never takes hold. The loss happens so early that you may not even know you're pregnant. However, the embryo produces hCG and can cause a false-positive on a pregnancy test.

How often does someone get pregnant on Nexplanon?

The implant is one of the best birth control methods out there — it's more than 99% effective. That means fewer than 1 out of 100 people who use Nexplanon will get pregnant each year. It doesn't get much better than that.