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What happens if neuropathy goes untreated?

Author

Rachel Ellis

Published Jan 17, 2026

If the underlying cause of peripheral neuropathy isn't treated, you may be at risk of developing potentially serious complications, such as a foot ulcer that becomes infected. This can lead to gangrene (tissue death) if untreated, and in severe cases may mean the affected foot has to be amputated.

Does neuropathy get worse if untreated?

If left untreated, the numbness, tingling, and burning caused by peripheral neuropathy will get worse over time. The damaged nerves will continue to send confusing messages to the brain more frequently until the spinal cord gets so used to sending the signals, it will continue to do it on its own.

What is end stage neuropathy?

Stage 5: Complete Loss of Feeling

This is the final stage of neuropathy, and it is where you've lost any and all feeling in your lower legs and feet. You do not feel any pain, just intense numbness. This is because there are no nerves that are able to send signals to your brain.

Can neuropathy affect your whole body?

Peripheral neuropathy means these nerves don't work properly. Peripheral neuropathy may occur because of damage to a single nerve or a group of nerves. It may also affect nerves in the whole body.

Can you become paralyzed from peripheral neuropathy?

Neuropathy is a disorder that prevents nerves from functioning properly. It can cause paralysis if a nerve is completely lacerated, although total paralysis is rare in people with neuropathy. Rather, the disease causes varying degrees of weakness, depending on the type and severity of the neuropathy.

43 related questions found

What is the life expectancy of someone with peripheral neuropathy?

There are several key factors that affect a patient's prognosis in familial amyloid polyneuropathy (FAP), but most people with the rare, inherited, progressive disease have a life expectancy of about 10 years after being diagnosed.

Can you live with neuropathy?

Treating Neuropathy

The good news for those living with neuropathy is that it is sometimes reversible. Peripheral nerves do regenerate. Simply by addressing contributing causes such as underlying infections, exposure to toxins, or vitamin and hormonal deficiencies, neuropathy symptoms frequently resolve themselves.

Is neuropathy fatal?

When those deposits build up, peripheral nerves start to malfunction, and the patient experiences peripheral neuropathy. The disease eventually involves sensory, motor and autonomic nerves, and it is fatal.”

Can neuropathy affect your walking?

Walking with a wobbly motion or even losing your balance can result from diabetic peripheral neuropathy. Wearing orthopedic shoes often helps with this. Loss of coordination is a common sign of diabetic peripheral neuropathy. Often, muscle weakness affects the ankle, which can affect your gait.

Why is neuropathy worse some days?

Stress and Emotions

Strenuous exercise and the accompanying soreness can contribute to nerve pain during the night. Living in a chronic state of stress will wreak havoc on your physical and mental health. High stress levels could be a reason why neuropathy is worse on some days, as well as when you take medications.

Does neuropathy shorten your life?

No matter what type of neuropathy you have, if you reach stage three, your injuries can lead to more severe infections, such as sepsis and gangrene. In the most severe cases, these infections may lead to amputation or death, so you need to seek immediate medical care.

Is walking good for peripheral neuropathy?

Walking can reduce the pain and other symptoms of neuropathy from the nerve damage in your feet and lower legs. Walking and other light aerobic exercises have various benefits for people affected by neuropathy, which is a wide range of conditions involving disease and damage to the peripheral nerves.

Can you have neuropathy without being a diabetic?

Because 60-70% of people with diabetes have some nervous system damage, there's a perception that only people with diabetes can develop peripheral neuropathy -- but that's not true. Because lots of other things can cause the condition, anyone can suffer from peripheral neuropathy.

What are the warning signs of neuropathy?

The Top 17 Peripheral Neuropathy Warning Signs and Symptoms

  • burning pain radiating in hands or feet.
  • pins and needles in the extremities.
  • numbness and tingling.
  • weakness in arms and legs.
  • a knotted feeling in the soles and palms.
  • pain from the lightest touches.
  • difficulty walking.
  • pain from the pressure of walking.

What are the symptoms of severe neuropathy?

Signs and symptoms of peripheral neuropathy might include:

  • Gradual onset of numbness, prickling or tingling in your feet or hands, which can spread upward into your legs and arms.
  • Sharp, jabbing, throbbing or burning pain.
  • Extreme sensitivity to touch.

What causes neuropathy to flare up?

It's usually caused by chronic, progressive nerve disease, and it can also occur as the result of injury or infection. If you have chronic neuropathic pain, it can flare up at any time without an obvious pain-inducing event or factor. Acute neuropathic pain, while uncommon, can occur as well.

Why does neuropathy get worse at night?

At night our body temperature fluctuates and goes down a bit. Most people tend to sleep in a cooler room as well. The thought is that damaged nerves might interpret the temperature change as pain or tingling, which can heighten the sense of neuropathy.

What can a neurologist do for neuropathy?

Treatment for Peripheral Neuropathy in Adults

Simple lifestyle changes help some people with peripheral neuropathy to manage their symptoms. Our neurologists prescribe medication to treat neuropathy. A procedure called plasma exchange can help some people with peripheral neuropathy achieve remission.

What doctor treats neuropathy in feet?

Everyone with symptoms of peripheral neuropathy of the feet should see a podiatrist. Podiatrists are doctors who are specially trained to preserve the health of the feet.

Is neuropathy considered a disability?

Neuropathy is considered a disability by the SSA. The SSA refers to a medical guide called the Blue Book when evaluating eligibility for Social Security disability benefits. Section 11.14 of the Blue Book lists the symptoms of peripheral neuropathy that might make you eligible for financial assistance.

Can neuropathy affect your eyes?

However, the answer to the question is, YES, neuropathy can affect the eyes. According to the website at E Medicine Health , there are two specific types of what is referred to as cranial neuropath and these are optic neuropathy and auditory neuropathy.

How do you calm down neuropathy?

Regular exercise, such as walking three times a week, can reduce neuropathy pain, improve muscle strength and help control blood sugar levels. Gentle routines such as yoga and tai chi might also help. Quit smoking.

How do people with neuropathy live a normal life?

The following suggestions can help you manage peripheral neuropathy:

  1. Take care of your feet, especially if you have diabetes. Check your feet daily for signs of blisters, cuts or calluses. ...
  2. Quit smoking. ...
  3. Eat healthy meals. ...
  4. Massage. ...
  5. Avoid prolonged pressure.

Can neuropathy affect your organs?

Neuropathy can affect nerves that control muscle movement (motor nerves) and those that detect sensations such as coldness or pain (sensory nerves). In some cases, it can affect internal organs, such as the heart, blood vessels, bladder, or intestines.

What is the difference between neuropathy and peripheral neuropathy?

Neuropathic Pain and Treatment Options

Neuropathic pain is often described as a tingling or burning sensation, and peripheral neuropathy often causes pain and numbness in the hands and feet. Symptoms may improve if the neuropathy has an underlying condition that can be cured or better managed.