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What happens if you take SSRIs when you don't need them?

Author

Rachel Ellis

Published Jan 18, 2026

There is new reason to be cautious about using popular antidepressants in people who are not really depressed. For the first time, research has shown that a widely used antidepressant may cause subtle changes in brain structure and function when taken by those who are not depressed.

What happens if a non depressed person takes antidepressants?

(If a person who isn't depressed takes antidepressants, they do not improve that person's mood or functioning - it's not a "happy pill.") Rarely, people experience apathy or loss of emotions while on certain antidepressants. When this happens, lowering the dose or switching to a different antidepressant may help.

Do SSRIs change your brain forever?

They work by immediately increasing the amount of serotonin in the brain and by causing long term changes in brain function. However it can take weeks of treatment before a patient feels any effect and both beneficial effects and side effects can persist after treatment is stopped.

Do SSRIs take away your personality?

Besides countering depression, the SSRI antidepressants may be capable of producing subtle changes in the personality traits of neuroticism and extraversion. This finding comes from a study reported in the December 2009 Archives of General Psychiatry.

Are SSRIs harmless?

Safety issues. SSRIs are generally safe for most people. However, in some circumstances they can cause problems. For example, high doses of citalopram may cause dangerous abnormal heart rhythms, so doses over 40 milligrams (mg) a day should be avoided according to the FDA and the manufacturer.

33 related questions found

Do SSRIs do more harm than good?

Our review supports the conclusion that antidepressants generally do more harm than good by disrupting a number of adaptive processes regulated by serotonin. However, there may be specific conditions for which their use is warranted (e.g., cancer, recovery from stroke).

Are SSRIs good for anxiety?

Selective serotonin reuptake inhibitors (SSRIs), which were designed to treat depression, are also effective for many anxiety disorders. They have revolutionized the treatment of anxiety, replacing chronic use of benzodiazepines (BZs). SSRIs are effective for OCD, PDs, phobias, PTSD, and GAD (see Table I).

Do SSRIs make you emotionless?

SSRI antidepressants are sometimes associated with something called emotional blunting. This can also include such symptoms as feeling indifferent or apathetic, being less able to cry and less able to experience the same degree of positive emotion as one normally would.

Can SSRIs make you fall out of love?

“Antidepressants tend to tone down the emotions. But they don't interfere with the ability to fall in love. No,” says Otto Kernberg, director of the Personality Disorders Institute at the New York Presbyterian Hospital and author of six books on love.

Can Paxil change your personality?

The researchers write that patients taking Paxil “reported 6.8 times as much change on neuroticism and 3.5 times as much change on extraversion as placebo patients matched for depression improvement.” Patients taking Paxil became “less shy, more vivacious ...

Do antidepressants shorten your life?

The analysis found that in the general population, those taking antidepressants had a 33 percent higher risk of dying prematurely than people who were not taking the drugs. Additionally, antidepressant users were 14 percent more likely to have an adverse cardiovascular event, such as a stroke or a heart attack.

Can SSRIs damage the brain?

Some research has suggested this type of drug aids in neuroplasticity. In other words, these drugs can affect how our minds organize and form synaptic connections. Other researchers believe this type of medication has no long-term effects on our brains once the individual stops using the drug.

Do SSRIs cause long-term damage?

During long-term SSRI therapy, the most troubling adverse effects are sexual dysfunction, weight gain, and sleep disturbance.

What happens if you take Zoloft and don't need it?

What Are the Effects of Taking Antidepressants Without Depression? Research shows that taking antidepressants if you're not depressed can alter brain function and structure, particularly the medication Zoloft.

Do I really need antidepressants?

Taking medicine for your depression can help you get your life back to normal, especially if you also get counselling. But if your symptoms are mild, lifestyle changes and counselling may be all you need. You don't need to be ashamed about taking antidepressants.

How long does it take for brain to return to normal after SSRI?

The process of healing the brain takes quite a bit longer than recovery from the acute symptoms. In fact, our best estimates are that it takes 6 to 9 months after you are no longer symptomatically depressed for your brain to entirely recover cognitive function and resilience.

Does emotional blunting from antidepressants go away?

By and large, those who no longer needed antidepressants experienced a reversal of emotional blunting, confirming the role that the drug plays in the side effect.

Do SNRIs cause emotional blunting?

It was estimated that about 40–60% of patients who suffered from MDD and were treated with either SSRIs or serotonin-noradrenaline reuptake inhibitors (SNRIs) had experienced some degrees of emotional blunting (20, 21).

Do antidepressants make you feel flat?

This refers to the drugs' effects — they cause the brain to produce more serotonin, a chemical that makes a person feel happier. In producing these feelings, however, antidepressants dull the intensity of all emotions. This is what's meant by feeling flat or emotionless.

Can you still cry on antidepressants?

Though the symptoms of depression have decreased, there may be a sense that other emotional responses – laughing or crying, for example – are more difficult to experience. This is termed “emotional blunting,” which is the experience of dulled emotional states caused by an antidepressant.

What happens if a normal person takes antidepressants?

There is new reason to be cautious about using popular antidepressants in people who are not really depressed. For the first time, research has shown that a widely used antidepressant may cause subtle changes in brain structure and function when taken by those who are not depressed.

What do SSRIs feel like?

Common side effects of selective serotonin reuptake inhibitors (SSRIs) and serotonin-noradrenaline reuptake inhibitors (SNRIs) can include: feeling agitated, shaky or anxious. feeling and being sick. indigestion and stomach aches.

How do I know if I need antidepressants for anxiety?

Signs that medication is making things worse include anxiety, panic attacks, insomnia, hostility, restlessness, and extreme agitation—particularly if the symptoms appear suddenly or rapidly deteriorate. If you spot the warning signs in yourself or a loved one, contact a doctor or therapist immediately.

What is the safest SSRI for anxiety?

Sertraline (Zoloft) has a more favorable safety profile compared to paroxetine. Sertraline is the safest SSRI for people with a history of heart problems. Sertraline is also considered safe in pregnancy, breastfeeding, and is approved for use in teens as well as adults.

Can SSRIs make anxiety worse?

More than 100 million people worldwide take selective serotonin reuptake inhibitors (SSRIs), such as Prozac and Zoloft, to treat depression, anxiety and related conditions, but these drugs have a common and mysterious side effect: they can worsen anxiety in the first few weeks of use, which leads many patients to stop ...