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What medications should not be taken with probiotics?

Author

James Craig

Published Jan 15, 2026

Some medications that may interact with certain probiotics include: antibiotics, antifungals (such as clotrimazole, ketoconazole, griseofulvin, nystatin).

Is it OK to take a probiotic with other medications?

Keep in mind that it's safe to take probiotics and antibiotics at the same time ( 1 ). If you take other medications or supplements, it's best to discuss potential interactions with your healthcare provider. That's because probiotics may increase their effectiveness ( 12 ).

Do probiotics affect blood pressure meds?

Conclusion. This meta-analysis found a moderate and statistically significant reduction for either SBP or DBP with probiotics supplement compared with controls. Thus, probiotics is a potential for the dietary treatment of hypertension.

When should you not take a probiotic?

Although probiotics are generally safe to use, findings of a review from 2017 suggest that children and adults with severe illnesses or compromised immune systems should avoid using probiotics. Some people with these conditions have experienced bacterial or fungal infections as a result of probiotic use.

Can you take Tylenol with probiotics?

No interactions were found between Children's Tylenol and Probiotic Formula.

36 related questions found

Can you take probiotics with anxiety medication?

A 2017 research review looking at how probiotics affect symptoms of depression found that taking a daily probiotic supplement seemed to help with symptoms of both depression and anxiety. Probiotics also seemed to work best when used in conjunction with other treatments, including medication and psychotherapy.

What are the dangers of taking probiotics?

Possible harmful effects of probiotics include infections, production of harmful substances by the probiotic microorganisms, and transfer of antibiotic resistance genes from probiotic microorganisms to other microorganisms in the digestive tract.

Can you take probiotics with cholesterol medicine?

It is safe to take For Cholesterol alongside any medicine or food supplement. In fact, probiotics generally have very few contraindications. Many people who take medication such as statins may also wish to take For Cholesterol. This is absolutely fine.

Can I take probiotics with amlodipine?

Interactions between your drugs

No interactions were found between amlodipine and Nature's Bounty Probiotic.

Can you take probiotics with metformin?

Can I take probiotics with metformin? Generally speaking, yes. And, some types of probiotics have been reported to help alleviate common negative gastrointestinal side effects (diarrhea, etc.) associated with metformin.

Can you take multivitamins with probiotics?

You might be concerned that taking a probiotic supplement at the same time as your morning vitamins or supplements might make one of the two less effective. Fear not, in most cases, taking probiotics should not affect the effectiveness of other supplements, such as your daily multivitamin or vice versa.

Do probiotics interfere with statins?

Patients with those compounds in their blood could be directed to other medications or different statins. Consuming probiotics might also alter the intestinal flora so that the balance of bacteria in the gut is tilted towards bacteria that do not produce chemicals that neutralize the effects of statins.

Can probiotics affect your heart?

Probiotics and heart health. Clinical research published earlier this year has found that probiotics can significantly improve health in those at risk of heart disease7. An important connection exists between the gut microbiome, probiotics and heart health8.

Can you take probiotics with acid reducers?

It is safe to take probiotics and antacids together, though each can interact with other medications. For this reason, a person should speak with a doctor before taking any kind of supplement. Probiotics may increase the effectiveness of antacids and may even be a viable replacement.

What are the signs you need probiotics?

6 signs you need a probiotic

  • You have allergies and asthma. ...
  • You suffer from one or more mood disorders. ...
  • You've had food poisoning. ...
  • You've taken antibiotics. ...
  • You're always getting sick. ...
  • You suffer from skin conditions such as acne and psoriasis.

Can I take Crestor with probiotics?

Interactions between your drugs

No interactions were found between Controlled Delivery Probiotic and rosuvastatin. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

What vitamins should you not take with statins?

Certain supplements may benefit people who take statins. For example, there is some evidence that taking supplements of coenzyme Q10 may reduce the muscle soreness that statins sometimes cause. However, taking niacin (vitamin B3) supplements along with a statin medication may worsen muscle soreness.

Is it OK to take vitamin D with statins?

Vitamin D supplement may have moderate or no effect on the dosage requirement or side effects of pravastatin, rosuvastatin and pitavastatin. Since vitamin D has mild HMG-CoA reductase activity, it will work synergistically with all statins.

Should I take probiotics in the morning or at night?

With more time in your gut, the good bacteria can get to work healing your digestive issues. And that's exactly what you want if you're investing in a supplement. The bottom line: The best time to take a probiotic is generally at nighttime before bed.

Can probiotics make acid reflux worse?

Probiotics do not increase stomach acid and may help protect against the ill effects of acid reflux. Lactobacillus johnsonii was shown to have the opposite effect on hydrochloric acid production in a study involving mice.

What happens when you take probiotics everyday?

One concern people often have is whether their digestive system will become 'lazy' if they take probiotics every day. But, rest assured, probiotics are not thought to be like laxatives which can cause the gut to become 'lazy' and reliant on them in order to function.

Can you take probiotics at the same time as antidepressants?

“Although generally safe and palatable, in clinical settings it cannot be recommended that probiotics replace antidepressant medications as the primary treatment for depressed patients. However, they could be potential (and palatable) adjunctive therapies.”

Can probiotics help panic attacks?

Taking a probiotic could reduce anxiety if it contains a specific type of bacteria. A new study published in PLoS One has found that, among the many strains of probiotics, Lactobacillus (L.) rhamnosus has the most evidence showing that it could significantly reduce anxiety.

Can probiotics make anxiety worse?

Then she found an article in Mental Health Daily about the side effects and adverse reactions to probiotics that people have reported. And there she found her answer. That if you take more than 20 billion CFUs (she was taking 400 billion CFUs) per day, you can get side effects. And anxiety is listed as one of them.

Do probiotics affect cholesterol?

Summary There is good evidence that certain probiotics, particularly Lactobacilli, can help reduce cholesterol. They do this by preventing cholesterol from being made and absorbed, as well as by helping break it down.