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What problems can amlodipine cause?

Author

Sarah Smith

Published Jan 21, 2026

The more common side effects that can occur with amlodipine include:

  • swelling of your legs or ankles.
  • tiredness or extreme sleepiness.
  • stomach pain.
  • nausea.
  • dizziness.
  • hot or warm feeling in your face (flushing)
  • irregular heart rate (arrhythmia)
  • very fast heart rate (palpitations)

What are the most common side effects of amlodipine?

Amlodipine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • swelling of the hands, feet, ankles, or lower legs.
  • headache.
  • upset stomach.
  • nausea.
  • stomach pain.
  • dizziness or lightheadedness.
  • drowsiness.
  • excessive tiredness.

What should you avoid when taking amlodipine?

Amlodipine Interactions with Alcohol

Combined use of alcohol and amlodipine may lead to some severe side effects like dizziness or lightheadedness. It is best to avoid alcohol when you are on amlodipine.

Can amlodipine cause neurological problems?

After another amlodipine dosage increase, the patient experienced a sudden onset of left-sided facial numbness, facial weakness, and a severe headache. The patient was admitted to rule out a possible cerebrovascular event or a metabolic neurologic process.

Why is amlodipine being recalled?

Citing defective bottles that may not seal appropriately and protect from moisture, Pfizer Inc. is recalling two lots of Caduet (amlodipine besylate/atorvastatin calcium) tablets. The recall was announced in the February 19, 2020, US Food and Drug Administration (FDA) Enforcement Report.

45 related questions found

Is amlodipine hard on the kidneys?

Amlodipine and lisinopril should not cause kidney damage and in fact are used to treat high blood pressure and slow the progression of chronic kidney disease (CKD).

Can I take vitamin D with amlodipine?

Interactions between your drugs

No interactions were found between amlodipine and Vitamin D3.

Does amlodipine cause memory loss?

Impairments in verbal-numerical reasoning: Amlodipine, calcium-channel blockers, diabetes drugs, iron, proton-pump inhibitors, sulfonamides. Impairments in memory: Amlodipine, calcium-channel blockers, nifedipine.

Can I take amlodipine occasionally?

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

Who should not take amlodipine?

Conditions: severe narrowing of the aortic heart valve. significantly low blood pressure. severe liver disease.

What is the safest blood pressure medicine?

Methyldopa, which works to lower blood pressure through the central nervous system, has the lowest risk of harming the mother and developing fetus. Other possible safe options include labetalol, beta-blockers, and diuretics.

Why should amlodipine be taken at night?

New research suggests that taking your blood pressure medication at bedtime may more effectively reduce your risk of illness or death due to heart and blood vessel disease. Timing of medication is important because blood pressure follows a daily rhythm. It rises higher during the day and falls at night when we sleep.

Is it OK to take multivitamins with amlodipine?

Using amLODIPine together with multivitamin with minerals can decrease the effects of amLODIPine. Talk with your doctor before using amLODIPine and multivitamin with minerals together. You may need a dose adjustment or need your blood pressure checked more often if you take both medications.

What is an alternative to amlodipine?

Nifedipine, lisinopril, losartan, and carvedilol are some amlodipine alternatives. Get the full list here. Amlodipine is a generic medication prescribed to treat high blood pressure. In addition to treating high blood pressure, amlodipine is approved to treat angina and other problems with coronary artery disease.

Does amlodipine cause a cough?

No, you probably won't have a cough when taking amlodipine. A cough wasn't a side effect reported in studies of the drug. But you may take other drugs together with amlodipine that can cause a cough. For example, angiotensin-converting enzyme (ACE) inhibitors may cause a cough.

Does amlodipine affect sleep?

Amlodipine oral tablet may cause extreme sleepiness. It can also cause other side effects.

How do I get off amlodipine?

If you have been using this medicine regularly for several weeks, do not suddenly stop using it. Stopping suddenly may cause your chest pain or high blood pressure to come back or get worse. Check with your doctor for the best way to reduce gradually the amount you are taking before stopping completely.

Do calcium channel blockers cause dementia?

The incidence of developing dementia in the CCB-exposure group was significantly lower than that in the matched comparator group (3.9 vs 6.9 per 10 3 person-years, P < 0.01). Table 1: Baseline characteristics between calcium channel blocker exposure group and comparator group.

What are the side effects of amlodipine besylate 5mg tab?

SIDE EFFECTS: Dizziness, lightheadedness, swelling ankles/feet, nausea, abdominal/stomach pain, or flushing may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. To lower your risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.

What nutrients does amlodipine deplete?

Another commonly used family of blood pressure medicines. Examples include; amlodipine, nifedipine, felodipine, diltiazem and verapamil. Nutrients that can be depleted by these medicines are potassium, calcium, vitamin D and possibly Co-Enzyme Q10.

Does orange juice interfere with amlodipine?

GENERALLY AVOID: Coadministration with orange, apple, or grapefruit juice may significantly decrease the oral bioavailability and renin-inhibiting effect of aliskiren.

Can I take amlodipine every other day?

How to take it. You'll usually take amlodipine once a day. You can take it at any time of day, but try to make sure it's around the same time every day.

Can amlodipine cause bowel problems?

The reported chronic gastrointestinal side effects from amlodipine include constipation, dyspepsia, dysphagia, diarrhea, flatulence and pancreatitis.

Does amlodipine cause depression?

Mood changes such as depression or anxiety. Difficulty sleeping (insomnia).

Can you take vitamin C and D with amlodipine?

No interactions were found between amlodipine and Vitamin C.