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Where does quinine come from in tonic water?

Author

Mia Kelly

Published Jan 09, 2026

Cinchona and malaria

The bitter flavouring of tonic water comes from an alkaloid called quinine which is extracted from the bark of the Andean fever tree (Cinchona spp.). The tree's remarkable curative properties were discovered as a fever remedy in South America in the early 17th century.

What is quinine water made of?

Quinine water was traditionally made from the bark of the cinchona tree. The bark of the quinquina tree was exported in massive amounts to Europe. It became a sort of miracle drug, even curing King Louis XIV of malaria. Because of trade restrictions, however, the seeds themselves were not allowed out of Peru.

What is the natural source of quinine?

Quinine is a bitter-tasting, crystalline white powder. It is obtained from the bark of the cinchona tree and belongs to the group of alkaloids. In medicine quinine is used to treat malaria and nocturnal leg cramps.

Can quinine in tonic water be harmful?

Tonic water contains no more than 83 mg of quinine per liter—a much lower concentration than the 500 to 1,000 mg in the therapeutic dose of quinine tablets. Drinking a few ounces of tonic water shouldn't be harmful, but it isn't likely to prevent your leg cramps.

Is it OK to drink tonic water every day?

According to the American Heart Association, excess levels of sodium (they recommend staying under 1,500 mg) can lead to water retention, along with puffiness, bloating, and weight gain. Our verdict: Avoid tonic water as a daily drink if you're concerned about your waistline.

35 related questions found

Can I buy quinine?

In the United States, quinine tablets are available only by prescription for the treatment of malaria (as Qualaquin). In other countries, quinine may be available for leg cramps by prescription or over-the-counter.

Which tonic water has the most quinine?

Which Brand Of Tonic Water Has The Most Quinine? The most quinine-containing tonic water is Fever-Tree Premium Indian Tonic Water, which is made with quinine from the Rwanda Congo border, spring water, and eight botanical flavors, including marigold and bitter orange extracts.

What does quinine do to the body?

Quinine is used to treat malaria caused by Plasmodium falciparum. Plasmodium falciparum is a parasite that gets into the red blood cells in the body and causes malaria. Quinine works by killing the parasite or preventing it from growing.

Does quinine have any health benefits?

Other than its use as an antimalarial drug, quinine doesn't have any health benefits. While quinine in tonic water has been used as a home remedy for nighttime leg cramps and muscle pain, there's no evidence that it works.

Does all Schweppes have quinine?

Tonic water in general and Schweppes tonic water, in particular, contains no more than 83 mg of quinine/liter. Schweppes quinine concentration is much less than the amount of quinine in the therapeutic dose of quinine tablets. Specifically, Schweppes quinine content is 67 mg/liter.

What drink has the most quinine?

Today, you can find quinine in some of your favorite beverages, most notably in tonic water. Historically, tonic water contained very high levels of quinine and was extremely bitter, requiring sugar and, at times, gin to improve the flavor profile.

Does Coke have quinine?

Quinine is sometimes added to cocaine for its bitter flavor. Thiamin, also known as vitamin B1.

What herbs contain quinine?

Although all cinchona species are good sources of quinine, C. succirubra and C. ledgeriana are the species containing the highest amount of quinine alkaloids - which is why they are the species of choice for cultivation today.

What drinks contain quinine?

Although the United States Food and Drug Administration banned its use for nocturnal leg cramps due to lack of safety and efficacy, quinine is widely available in beverages including tonic water and bitter lemon.

Do all tonic water have quinine?

Medicinal tonic water originally contained only carbonated water and a large amount of quinine; most modern tonic waters contain comparatively less quinine, and are often enhanced by citrus flavors.

What is in Schweppes?

Ingredients Carbonated Water, High Fructose Corn Syrup, Citric Acid, Sodium Benzoate (Preservative), Quinine, Natural Flavors.

Can you buy quinine water?

As a food additive, quinine offers a bitter taste. Manufacturers usually add it to tonic water. Some people use tonic water to help treat nighttime leg cramps, but there is little evidence to suggest that this is effective. Tonic water is available for purchase online.

Is tonic water the same as club soda?

Club soda is infused with carbon dioxide and mineral salts. Similarly, seltzer is artificially carbonated but generally doesn't contain added minerals. Tonic water is also carbonated but contains added quinine and sugar, which means it provides calories.

Is quinine a mineral?

While it is unclear if use during pregnancy causes harm to the baby, treating malaria during pregnancy with quinine when appropriate is still recommended. Quinine is an alkaloid, a naturally occurring chemical compound.

Why was quinine taken off the market?

In early 2007, FDA banned all prescription quinine products other than Qualaquin. FDA acted in this manner because of a perception that quinine is not effective for this condition and that its risk potential far exceeds its efficacy potential.

Who invented quinine?

In 1820, quinine was extracted from the bark, isolated and named by Pierre Joseph Pelletier and Joseph Caventou. Purified quinine then replaced the bark as the standard treatment for malaria [5].

Is quinine an antibiotic?

Quinine is a prescription drug used as an antimalarial drug indicated only for the treatment of uncomplicated Plasmodium falciparum malaria.

Does Fever-Tree contain quinine?

By blending luscious botanical oils with spring water and quinine of the highest quality from the 'fever trees' from the eastern hill ranges of the Democratic Republic of Congo, we have created a delicious, award-winning tonic water.

Does Canada Dry tonic water have quinine?

Product Details. Canada Dry Tonic Water delivers a clear, sparkling taste with a distinct touch of quinine and is caffeine free. Transform your favorite spirit into a classic concoction and add a refreshing splash of bubbly effervescence with Canada Dry Tonic Water.

Why does tonic water glow under a blacklight?

The answer is surprisingly simple: Tonic water actually contains the chemical quinine, which fluoresces under certain light and makes tonic water glow.